2026-03-10T12:06:26Z https://kutarr.kochi-tech.ac.jp/oai

oai:kutarr.kochi-tech.ac.jp:00000218 2023-05-15T13:41:24Z 5

Ring construction via pseudo-intramolecular hydrazonation using bifunctional δ-keto nitrile Hirao, Shotaro Kobiro, Kazuya Sawayama, Jun Saigo, Kazuhiko Nishiwaki, Nagatoshi An α-nitro-δ-keto nitrile efficiently reacted with hydrazines at room temperature, even in the absence of a catalyst, to afford the corresponding hydrazones; the reactions proceeded through a pseudo-intramolecular process. The hydrazone derived from hydrazine monohydrate underwent water-assisted cyclization, which yielded the corresponding diazepine. The hydrazones derived from 4-nitrophenylhydrazine and 2,4-dinitrophenylhydrazine were converted into pyridazines upon being heated in DMSO. journal article Elsevier Ltd. 2012 AM application/pdf Tetrahedron Letters 1 53 82 85 https://kutarr.kochi-tech.ac.jp/record/218/files/27-20.pdf http://hdl.handle.net/10173/1340 https://kutarr.kochi-tech.ac.jp/records/218 eng 10.1016/j.tetlet.2011.10.159