@article{oai:kutarr.kochi-tech.ac.jp:00000218, author = {Hirao, Shotaro and Kobiro, Kazuya and Sawayama, Jun and Saigo, Kazuhiko and Nishiwaki, Nagatoshi}, issue = {1}, journal = {Tetrahedron Letters}, month = {}, note = {An α-nitro-δ-keto nitrile efficiently reacted with hydrazines at room temperature, even in the absence of a catalyst, to afford the corresponding hydrazones; the reactions proceeded through a pseudo-intramolecular process. The hydrazone derived from hydrazine monohydrate underwent water-assisted cyclization, which yielded the corresponding diazepine. The hydrazones derived from 4-nitrophenylhydrazine and 2,4-dinitrophenylhydrazine were converted into pyridazines upon being heated in DMSO.}, pages = {82--85}, title = {Ring construction via pseudo-intramolecular hydrazonation using bifunctional δ-keto nitrile}, volume = {53}, year = {2012} }