| Item type |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2010-11-22 |
| タイトル |
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|
タイトル |
Ion irradiation in liquid of μm3 region for cell surgery |
| 言語 |
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|
言語 |
eng |
| キーワード |
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|
主題Scheme |
Other |
|
主題 |
biological effects of ionising particles |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
cellular biophysics |
| キーワード |
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|
主題Scheme |
Other |
|
主題 |
ion beam effects |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 著者 |
Iwai, Yoshio
Ikeda, Tokihiro
Kojima, Takao M.
Yamazaki, Yasunori
Maeshima, Kazuhiro
Imamoto, Naoko
Kobayashi, Tomohiro
Nebiki, Takuya
Narusawa, Tadashi
Pokhil, Grigory P.
|
| 抄録 |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
We present here a cell surgery scheme involving selective inactivation or disruption of cellular structures. Energetic ions are injected into a cell through a tapered glass capillary like a microinjection method. A slight but essential difference from microinjection is that a thin window is prepared at the outlet so that no liquid material can flow in or back through the outlet while still allowing energetic ions to penetrate into the cell. An ∼ MeV He ion beam from such a capillary having 10 μm outlet diameter inactivated a selected volume ( ∼ μm3) of fluorescent molecules located in a HeLa cell nucleus. |
| 書誌情報 |
Applied Physics Letters
巻 92,
号 2,
p. 023509-1-023509-3,
発行日 2008-01-17
|
| ISSN |
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収録物識別子タイプ |
ISSN |
|
収録物識別子 |
0003-6951 |
| 書誌レコードID |
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|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA00543431 |
| DOI |
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|
関連タイプ |
isIdenticalTo |
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|
識別子タイプ |
DOI |
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関連識別子 |
10.1063/1.2834695 |
| 権利 |
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|
権利情報 |
Copyright 2008 American Institute of Physics. This article may be downloaded for personal use only. Any other use requires prior permission of the author and the American Institute of Physics. The following article appeared in Appl. Phys. Lett. 92, 023509 (2008) and may be found at http://link.aip.org/link/?apl/92/023509 |
| 著者版フラグ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| 出版者 |
|
|
出版者 |
American Institute of Physics |
| 関係URI |
|
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|
識別子タイプ |
URI |
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|
関連識別子 |
http://link.aip.org/link/?apl/92/023509 |
|
|
関連名称 |
http://link.aip.org/link/?apl/92/023509 |
APL_92_2_023509.pdf (491.8 kB)
