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Synthesis of a new type of artificial nucleic acid derived from optically active serine
http://hdl.handle.net/10173/967
http://hdl.handle.net/10173/9671769a928-1acb-4b86-84c1-4b4171520395
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
NARS_1_1_187.pdf (145.0 kB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||
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| 公開日 | 2013-03-29 | |||||
| タイトル | ||||||
| タイトル | Synthesis of a new type of artificial nucleic acid derived from optically active serine | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| 著者 |
Wada, Takeshi
× Wada, Takeshi× Tsuneyama, Toshikazu× Saigo, Kazuhiko |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | This paper describes the synthesis of a new type of nucleic acid analog derived from L-serine with ester linkages. The monomer unit bearing thymine base was synthesized from L-serine ethyl ester by a three-step reaction in good yield without racemization. 3-Nitro-l,2,4-triazol-l-yl-tris(pyrrolidin-l-yl)phosphonium hexafluorophosphate (PyNTP) was found to be highly effective for the rapid ester bond formation without racemization. 2-Phenyl-2-(trimethylsilyl)ethyl group was successfully employed as a carboxyl protecting group in solution-phase synthesis. | |||||
| 書誌情報 |
Nucleic Acids Research Supplement 巻 1, 号 1, p. 187-188, 発行日 1905-06-23 |
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| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 0261-3166 | |||||
| DOI | ||||||
| 関連タイプ | isIdenticalTo | |||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.1093/nass/1.1.187 | |||||
| 権利（URI） | ||||||
| 権利情報 | http://nass.oxfordjournals.org/content/1/1/187 | http://nass.oxfordjournals.org/content/1/1/187 | |||||
| 著者版フラグ | ||||||
| 出版タイプ | VoR | |||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
| 出版者 | ||||||
| 出版者 | Oxford University Press | |||||
