| Item type |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2013-03-29 |
| タイトル |
|
|
タイトル |
Synthesis of a new type of artificial nucleic acid derived from optically active serine |
| 言語 |
|
|
言語 |
eng |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 著者 |
Wada, Takeshi
Tsuneyama, Toshikazu
Saigo, Kazuhiko
|
| 抄録 |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
This paper describes the synthesis of a new type of nucleic acid analog derived from L-serine with ester linkages. The monomer unit bearing thymine base was synthesized from L-serine ethyl ester by a three-step reaction in good yield without racemization. 3-Nitro-l,2,4-triazol-l-yl-tris(pyrrolidin-l-yl)phosphonium hexafluorophosphate (PyNTP) was found to be highly effective for the rapid ester bond formation without racemization. 2-Phenyl-2-(trimethylsilyl)ethyl group was successfully employed as a carboxyl protecting group in solution-phase synthesis. |
| 書誌情報 |
Nucleic Acids Research Supplement
巻 1,
号 1,
p. 187-188,
発行日 1905-06-23
|
| ISSN |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
0261-3166 |
| DOI |
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|
関連タイプ |
isIdenticalTo |
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|
識別子タイプ |
DOI |
|
|
関連識別子 |
10.1093/nass/1.1.187 |
| 権利（URI） |
|
|
権利情報 |
http://nass.oxfordjournals.org/content/1/1/187 | http://nass.oxfordjournals.org/content/1/1/187 |
| 著者版フラグ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| 出版者 |
|
|
出版者 |
Oxford University Press |
NARS_1_1_187.pdf (145.0 kB)
