| Item type |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2017-03-24 |
| タイトル |
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|
タイトル |
Development of variously functionalized nitrile oxides |
| 言語 |
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|
言語 |
eng |
| キーワード |
|
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主題Scheme |
Other |
|
主題 |
acylnitrile oxide |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
amide |
| キーワード |
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|
主題Scheme |
Other |
|
主題 |
formylnitrile oxide |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
functionalized nitrile oxide |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
Weinreb amide |
| 資源タイプ |
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資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 著者 |
Asahara, Haruyasu
Arikiyo, Keita
Nishiwaki, Nagatoshi
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| 抄録 |
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内容記述タイプ |
Abstract |
|
内容記述 |
N-Methylated amides (N,4-dimethylbenzamide and N-methylcyclohexanecarboxamide) were systematically subjected to chemical transformations, namely, N-tosylation followed by nucleophilic substitution. The amide function was converted to the corresponding carboxylic acid, esters, amides, aldehyde, and ketone upon treatment with hydroxide, alkoxide, amine, diisobutylaluminium hydride and Grignard reagent, respectively. In these transformations, N-methyl-N-tosylcarboxamides behave like a Weinreb amide. Similarly, N-methyl-5-phenylisoxazole-3-carboxamide was converted into 3-functionalized isoxazole derivatives. Since the amide was prepared by the cycloaddition reaction of ethynylbenzene and N-methylcarbamoylnitrile oxide, the nitrile oxide served as the equivalent of the nitrile oxides bearing a variety of functional groups such as carboxy, alkoxycarbonyl, carbamoyl, acyl and formyl moieties. |
| 書誌情報 |
Beilstein Journal of Organic Chemistry
巻 11,
p. 1241-1245,
発行日 2015-07
|
| DOI |
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関連タイプ |
isIdenticalTo |
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識別子タイプ |
DOI |
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関連識別子 |
10.3762/bjoc.11.138 |
| 権利 |
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|
権利情報 |
© 2015 Asahara et al; licensee Beilstein-Institut. |
| 権利 |
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|
権利情報 |
This is an Open Access article under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
| 権利 |
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|
権利情報 |
The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (http://www.beilstein-journals.org/bjoc) |
| 権利（URI） |
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|
権利情報 |
https://creativecommons.org/licenses/by/2.0/ | https://creativecommons.org/licenses/by/2.0/ |
| 著者版フラグ |
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|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| 出版者 |
|
|
出版者 |
Beilstein-Institut |
28-46.pdf (251.6 kB)
