{"_buckets": {"deposit": "a58d3902-dba5-433b-b3d9-bc5a224dc3bf"}, "_deposit": {"created_by": 2, "id": "129", "owners": [2], "pid": {"revision_id": 0, "type": "depid", "value": "129"}, "status": "published"}, "_oai": {"id": "oai:kutarr.kochi-tech.ac.jp:00000129", "sets": ["5"]}, "author_link": ["462", "464", "463", "461", "460"], "item_2_biblio_info_7": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2003-06-20", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "12", "bibliographicPageEnd": "1636", "bibliographicPageStart": "1631", "bibliographicVolumeNumber": "14", "bibliographic_titles": [{"bibliographic_title": "Tetrahedron: Asymmetry"}]}]}, "item_2_description_4": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "The resolution of racemic 3-(methylamino)-1-(2-thienyl)propan-1-ol (3), a new key intermediate for duloxetine (1), was studied.  The conditions were optimized for an industrial-scale resolution of 3 by using (S)-mandelic acid (4) as a resolving agent and 2-butanol containing two equimolar amounts of water as a solvent.  The (S)-3･(S)-4･H2O diastereomeric salt was crystallized to give pure (S)-3 with \u003e99.9% ee after liberation of the amine.  Absolute configuration of liberated (-)-3 was determined as (S)-form by X-ray crystallography.", "subitem_description_type": "Abstract"}]}, "item_2_publisher_35": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "Elsevier"}]}, "item_2_relation_13": {"attribute_name": "DOI", "attribute_value_mlt": [{"subitem_relation_type": "isVersionOf", "subitem_relation_type_id": {"subitem_relation_type_id_text": "10.1016/S0957-4166(03)00315-X", "subitem_relation_type_select": "DOI"}}]}, "item_2_relation_44": {"attribute_name": "関係URI", "attribute_value_mlt": [{"subitem_relation_name": [{"subitem_relation_name_text": "http://www.sciencedirect.com/science/journal/09574166"}], "subitem_relation_type_id": {"subitem_relation_type_id_text": "http://www.sciencedirect.com/science/journal/09574166", "subitem_relation_type_select": "URI"}}]}, "item_2_rights_14": {"attribute_name": "権利", "attribute_value_mlt": [{"subitem_rights": "© 2003 Elsevier Science Ltd. All rights reserved."}]}, "item_2_source_id_11": {"attribute_name": "書誌レコードID", "attribute_value_mlt": [{"subitem_source_identifier": "AA1074621X", "subitem_source_identifier_type": "NCID"}]}, "item_2_source_id_9": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "0957-4166", "subitem_source_identifier_type": "ISSN"}]}, "item_2_version_type_18": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_ab4af688f83e57aa", "subitem_version_type": "AM"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Sakai, Kenichi"}], "nameIdentifiers": [{"nameIdentifier": "460", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Sakurai, Rumiko"}], "nameIdentifiers": [{"nameIdentifier": "461", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Yuzawa, Atsushi"}], "nameIdentifiers": [{"nameIdentifier": "462", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kobayashi, Yuka"}], "nameIdentifiers": [{"nameIdentifier": "463", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Saigo, Kazuhiko"}], "nameIdentifiers": [{"nameIdentifier": "464", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2019-02-13"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "ttrasy_14_1631.pdf", "filesize": [{"value": "146.3 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 146300.0, "url": {"label": "ttrasy_14_1631.pdf", "url": "https://kutarr.kochi-tech.ac.jp/record/129/files/ttrasy_14_1631.pdf"}, "version_id": "ce348489-0f39-4d32-bc2c-dfe5cab982cc"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Resolution of 3-(methylamino)-1-(2-thienyl)propan-1-ol, a new key intermediate for duloxetine, with (S)-mandelic acid", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Resolution of 3-(methylamino)-1-(2-thienyl)propan-1-ol, a new key intermediate for duloxetine, with (S)-mandelic acid"}]}, "item_type_id": "2", "owner": "2", "path": ["5"], "permalink_uri": "http://hdl.handle.net/10173/724", "pubdate": {"attribute_name": "公開日", "attribute_value": "2011-08-30"}, "publish_date": "2011-08-30", "publish_status": "0", "recid": "129", "relation": {}, "relation_version_is_last": true, "title": ["Resolution of 3-(methylamino)-1-(2-thienyl)propan-1-ol, a new key intermediate for duloxetine, with (S)-mandelic acid"], "weko_shared_id": -1}